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Compound May Pose Health Risk to Women and Young G
amatullah
04/16/03 at 21:07:23
EPA Probes Widely Used Chemical
Compound May Pose Health Risk to Women and Young Girls

By Eric Pianin
Washington Post Staff Writer
Tuesday, April 15, 2003; Page A05


The Environmental Protection Agency yesterday launched an expedited
investigation of a chemical compound widely used for decades in
manufacturing Teflon-coated cookware, water- and stain-resistant
clothing, cosmetics and scores of other products, to determine
whether it poses a serious health risk to women of childbearing age
and young girls.

The chemical, perfluorooctanoic acid (PFOA), is toxic and persistent
in the environment and has been detected in small doses of the
bloodstreams of the vast majority of humans tested for it. There has
been growing concern about the effects of this compound for several
years, but yesterday's announcement suggested the government is
taking the problem more seriously and eventually might regulate the
chemical.

EPA officials became highly concerned late last year after reviewing
a study by 3M, which once manufactured PFOA. It found that laboratory
rats exposed to the synthetic chemical lost weight and experienced
delayed sexual maturation, and that an inordinate number of their
offspring died prematurely.

Now officials say they are conducting the most extensive scientific
assessment yet of the perfluorochemical family to determine whether
the substances may cause comparable sexual reproductive and
developmental damage to women and girls. PFOA has also been linked to
testicular, liver and pancreatic cancer in animals, and EPA officials
will investigate whether the chemical may be carcinogenic in humans.

"The fact that PFOA is present in humans is of interest and concern
to us," said Stephen L. Johnson, assistant administrator of the EPA's
Office of Prevention, Pesticides and Toxic Substances. "How the
levels in humans do or don't relate to the laboratory animal effects
we are seeing is what we're trying to sort out."

Johnson and other EPA officials cautioned, however, that there is
much they don't understand about the effects of PFOA, and that the
EPA may be many months away from determining whether the chemical
poses an unreasonable public risk.

Sensitive to the potential economic effects the investigation could
have on the multibillion-dollar perfluorochemical industry, Johnson
repeatedly told reporters that "the EPA does not believe there is any
reason for consumers to stop using any consumer or industrial related
products."

Until recent years, the EPA paid relatively scant attention to the
chemical, which is used to produce such world-famous brands as
Teflon, Stainmaster, Scotchgard and Gore-Tex, despite
environmentalists' warnings that it might eventually rival DDT, PCBs
and dioxin as a dangerous global chemical contaminant that is
impossible to eradicate.

"The public should have known about problems with this Teflon
chemical 30 years ago," said Kris Thayer, senior scientist for the
Washington-based Environmental Working Group. "What's outrageous is
that the law governing toxic chemicals allows DuPont and other big
companies to pollute our blood and environment first, and get around
to asking basic scientific questions decades later."

Delaware-based DuPont and three other overseas chemical companies
manufacture PFOA, which is used as a processing aid in the
manufacture of substances that keep food from sticking to pots and
pans, that repels stains on furniture and rugs, and that makes rain
roll off coats. Industry makes use of the slippery, heat-stable
properties of these chemicals to manufacture everything from
airplanes and computers to cell phones, cosmetics and household
cleaners.

Yesterday, DuPont reaffirmed its position that there is no evidence
indicating adverse human health effects related to low levels of
exposure to PFOA.

"We share the EPA's desire to safeguard human health and the
environment, and respect the position that there are still questions
to be addressed," said Richard Angiullo, vice president and general
manager for DuPont Fluoroproducts. "DuPont, along with other
companies, has voluntarily committed to EPA to provide the necessary
research to help address those questions. We also have led industry
in reducing emissions of PFOA."

Manufacturers including DuPont are not required to monitor or report
emissions of PFOA or related chemicals into the air, water or
landfills because the compound is not regulated under the federal
Toxic Substances Control Act.

In May 2000, 3M Co. announced that it would stop making many of its
well-known Scotchgard stain-repellent products after finding that one
of the chemical compounds used to make the products --
perfluorooctane sulfonate -- persists in the environment and is found
widely in the bloodstreams of people worldwide. 3M also stopped
manufacturing PFOA , leaving the U.S. market to DuPont.

As part of its action, the EPA formally released a preliminary risk
assessment, raising concerns about the potential links between PFOA
and reproductive and developmental problems in women. The agency also
invited industry groups, environmentalists and other interested
parties to help negotiate one or more consent agreements concerning
the control of small fluorine-containing synthetic substances
called "telomers," which may metabolize or degrade into PFOA.

© 2003 The Washington Post Company
Re: Compound May Pose Health Risk to Women and You
amatullah
04/16/03 at 21:10:21
Another thing I read seems to indicate that anti-bacterial soap may not be our best option:

Fears over antibacterial ingredient


Antibacterial soaps can contain triclosan
Exposure to sunlight could turn triclosan, an ingredient of antibacterial soaps, into a polluting chemical, claims research.
And there are fears that normal sewage treatment procedures could convert triclosan into something even more toxic.

Antibacterial home cleaning products are becoming more popular, even though there is limited evidence that they are effective.

Triclosan is commonly the active ingredient in these.

Scientists already knew that under certain laboratory conditions, it could be converted into a mild dioxin.

Dioxins are a group of similar chemicals which have been linked with health problems by experts.

They do not degrade over time, and can accumulate in body tissues to cause a larger effect over time.

Researchers at the University of Minnesota found that when triclosan in water was exposed to sunlight, it was chemically converted into a dioxin.

This reaction produces only a very mildly toxic chemical - perhaps 150,000 times less toxic than the types of dioxin considered the most dangerous.

Bigger problem

However, the scientists believe that triclosan-tainted water treated with chlorine at water treatment plants could then be broken down into something far more potent.

Dr Kristopher McNeill, one of the researchers, said: "Repeated exposure to chlorine could chlorinate triclosan.

"After chlorinated triclosan is discharged, sunlight could convert it into more toxic dioxins.

"Such a process might be a source of highly toxic dioxin in the environment."

Ban attempt

His colleague, Dr William Arnold, said: "This study shows that the disappearance of a pollutant such as triclosan doesn't necessarily mean an environmental threat has been removed.

"It may just have converted into another threat.

"The fact that this conversion can happen in surface layers of rivers may not cause harm by itself, but it suggests that more serious reactions - leading to more toxic forms of dioxin - may also happen."

The researchers said that even low levels of high toxicity dioxin were a problem because of its tendency to accumulate through the food chain.

Clare Oxborrow, from Friends of the Earth, said that there had already been efforts to get triclosan banned.

She said: "We would have concerns about anything which accumulates in the body in the way this does.

"Early studies have also shown that it may have some 'endocrine disrupting' - gender bending - effects on animals."

http://news.bbc.co.uk/2/hi/health/2950867.stm


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